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July 31, 2020

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Accelerating the publication of peer-reviewed science

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This Collection highlights content published across the PLOS journals relating to the COVID-19 pandemic.

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cell biology

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Suarez-Arnedo and colleagues develop a plugin for ImageJ that standardizes and automates quantification of in vitro wound parameters. The tool can use images from light field, phase contrast, and fluorescence microscopes and can analyze individual images or stacks.

Image credit: pone.0232565

An image J plugin for the high throughput image analysis of in vitro scratch wound healing assays

07/29/2020

Cardiovascular Biology

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Using the CRISPR/Cas9 technology in the amphibian 蜂鸟ⅴpn安卓下载, Smith and colleagues pinpoint the specific region of the ADP-ribosylhydrolase-like 1 gene that plays a critical role during heart formation.

Image credit: Smith and colleagues, pone.0235433

Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site

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Biophysics

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Han and colleagues use template-based and ab initio modelling techniques combined with molecular dynamics simulations in a complex membrane to identify key protein-lipid interactions between phospholipase D2 and the lipid PIP2.

Image credit: pone.0236201

PLD2–PI(4,5)P2 interactions in fluid phase membranes: Structural modeling and molecular dynamics simulations

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Pereira Cruz and colleagues combine archaeological records with inventories of forest composition to find that contemporary distribution of trees is linked with Pre-colonial habitation in Brazil.

Image credit: Courtesy NASA/JPL-Caltech

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07/23/2020

Microbiology

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Barros and colleaugues explore the interactions of four types of silica nanoparticles with Pseudomonas fluorescens biofilm matrices, and their use for future anti-biofilm applications.

Interactions between functionalised silica nanoparticles and Pseudomonas fluorescens biofilm matrix: A focus on the protein corona

Image credit: pone.0236441

07/23/2020

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The authors use a cuvette system to enable simultaneous real-time monitoring of several parameters that are indicative of the physiological status of the photosynthetic apparatus of two types of model organism—cyanobacteria and microalgae.

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06/24/2020

Everyone BLOg

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Associate Editor Joseph Donlan discusses news and research from the Physcial Sciences.

Building a home for the Physical Sciences at PLOS ONE

Image credit: Jill Hemman, CC-BY 2.0

07/23/2020

Infectious Disease

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Norovirus transmission mediated by asymptomatic family members in households

Image credit: Global Panorama

07/27/2020

Machine learning

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Wijeyakulasuriya and colleagues adapt machine learning and deep learning approaches to introduce models of animal movement with increased predictive power.

Machine learning for modeling animal movement

Image credit: Wikimedia Commons

07/27/2020

cell biology

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Tullis and colleagues demonstrate K42M and K42R mutations interfer with ATP binding comparably, supporting their interchangeable use for dissecting the role of CaMKII.

The CaMKII K42M and K42R mutations are equivalent in suppressing kinase activity and targeting

Image credit: pone.0236478

07/20/2020

Epidemiology

Cardiovascular disease risk among transgender women living with HIV in the United States

Gosiker and colleagues examine the prevalence of elevated 10-year cardiovascular disease risk among transgender women using data from a collaboration of HIV clinical sites in the United States.

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